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Research and Application of Medical Polyetheretherketone as Bone Repair Material.
Pu, Feifei; Yu, Yihan; Zhang, Zhicai; Wu, Wei; Shao, Zengwu; Li, Chao; Feng, Jing; Xue, Longjian; Chen, Fengxia.
Affiliation
  • Pu F; Department of Orthopedics, Traditional Chinese and Western Medicine Hospital of Wuhan (Wuhan No.1 Hospital), Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430022, China.
  • Yu Y; Department of Orthopedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430022, China.
  • Zhang Z; Department of Orthopedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430022, China.
  • Wu W; Department of Orthopedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430022, China.
  • Shao Z; Department of Orthopedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430022, China.
  • Li C; Department of Orthopedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430022, China.
  • Feng J; Department of Orthopedics, Traditional Chinese and Western Medicine Hospital of Wuhan (Wuhan No.1 Hospital), Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430022, China.
  • Xue L; School of Power and Mechanical Engineering, Wuhan University, Wuhan, Hubei, 430072, China.
  • Chen F; Department of Radiation and Medical Oncology, Zhongnan Hospital, Wuhan University, Wuhan, Hubei, 430071, China.
Macromol Biosci ; 23(9): e2300032, 2023 09.
Article in En | MEDLINE | ID: mdl-37088909
ABSTRACT
Polyetheretherketone (PEEK) can potentially be used for bone repair because its elastic modulus is similar to that of human natural bone and good biocompatibility and chemical stability. However, its hydrophobicity and biological inertness limit its application in the biomedical field. Inspired by the composition, structure, and function of bone tissue, many strategies are proposed to change the structure and functionality of the PEEK surface. In this review, the applications of PEEK in bone repair and the optimization strategy for PEEK's biological activity are reviewed, which provides a direction for the development of multifunctional bone repair materials in the future.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polyethylene Glycols / Polymers Limits: Humans Language: En Journal: Macromol Biosci Journal subject: BIOQUIMICA Year: 2023 Document type: Article Affiliation country:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polyethylene Glycols / Polymers Limits: Humans Language: En Journal: Macromol Biosci Journal subject: BIOQUIMICA Year: 2023 Document type: Article Affiliation country: